FAQs

What is T Lab Inc?

We are a CLIA certified clinical lab offering specialized blood and skin tests utilizing advanced tissue staining and microscopy techniques.

What tests to you offer?

We currently offer two types of tests using blood specimens (BNR and BMIP1) and one test using small skin biopsies (SMIP1).

The following are answers to Frequently Asked Questions we typically receive from physicians, patients and the general public who are interested in the tests we offer. If you have a question that is not addressed here, we would greatly appreciate it if you would take a few minutes to send it to us via the "Contact Us" box on the home page.

What is the BNR test?

The BNR test looks at a specially prepared sample of blood to identify the presence of biofilm (B), neutrophil degranulation (N), red blood cell inclusions (R).  The test requires a sample of whole blood, which is prepared on a slide and studied under a high-resolution microscope.  Results can include estimated biofilm load, degree of neutrophil activation, and indications of possible infection as seen in red blood cell morphology. 

Biofilm load - Some bacteria and fungi form biofilms when they begin to grow in a colony. The formation of biofilms within the vascular system can be indicative of a persistent infection. Biofilm formation reduces the effectiveness of antibiotics and can allow bacteria to persist after symptoms have resolved from standard treatments.

Neutrophil degranulation - Neutrophil lysis creates neutrophilic extracellular traps (NETS) composed of nucleic acids from within the neutrophil. When neutrophils encounter pathogens they often release these NETS as a way to fight the infection. Translational Medicine Group suspects that these NETS can become the seeds for biofilm formation by providing a surface for bacteria to adhere, biofilm in fact often contains nucleic acid. 

 

RBC morphology - Deformed RBCs can be indicative of the presence of microbes that infect and parasitize red blood cells. Red blood cell morphology can be altered by several factors.
 

Lab Inc

910 Clopper Road, Suite 220S, Gaithersburg, MD 20878

(240) 696-2788

(c) 2020 T Lab Inc